Pre-clinical and clinical trails
Deciding whether a drug is ready for clinical trials (the so-called move from bench to bedside) involves extensive preclinical studies that yield preliminary efficacy, toxicity, pharmacokinetic and safety information. Wide doses of the drug are tested using in vitro (test tube or cell culture) and in vivo (animal) experiments, and it is also possible to perform in silico profiling using computer models of the drug–target interactions.
Much like for clinical trials, there are certain types of trials that have to be done, such as toxicology studies in most cases, and other trials that are specific to the particular study compound or question. Understanding that the goal of preclinical trials is to move into the clinical stage is key and the studies should be designed around that goal. Watch our online seminar on moving from preclinical to clinical trials.
Clinical trial phases:
The entire process of moving a drug from design to clinical trials takes 10 to 12 years on average. Let’s take a closer look at each stage to better understand what goes into early clinical development and preparation for approval of a drug.
- drug development
- phase I trial
- clinical studies
Related Conference of Pre-clinical and clinical trails
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Pre-clinical and clinical trails Conference Speakers
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- Pharmacokinetics and Pharmacodynamics of Antimicrobial Drugs - Antibiotics Resistance 2024 (Canada)
- Pharmacological Advances and Drug Development - NURSING PHARMACOLOGY 2024 (Netherlands)
- Pharmacological Approaches to Myocardial Ischemia - Cardiovascular-2025 (France)
- Pharmacological Management of Cardiovascular Risk Factors - Cardiovascular-2025 (France)
- Pharmacological Sciences - Pharma Europe 2025 (Italy)
- Pharmacology - Drug Safety 2024 (France)
- Pharmacology - Pharmacoepidemiology Congress 2024 (Canada)
- Pharmacology - Pharmatech 2025 (Canada)
- Pharmacology & Toxicology - Antibiotics Resistance 2024 (Canada)
- Pharmacology and Toxicology - MedTech-2024 (Switzerland)
- Pharmacology and Toxicology - PHARMA MEDICINAL CHEMISTRY 2025 (Canada)
- Pharmacology of Addiction and Substance Abuse - Pharmacology-2024 (France)
- Pharmacology of Aging and Geriatric Medicine - Pharmacology-2024 (France)
- Pharmacology of Antimicrobial Resistance - Pharmacology-2024 (France)
- Pharmacology of Cancer Immunotherapy - Pharmacology-2024 (France)
- Pharmacology of Cardiovascular Therapeutics - Pharmacology-2024 (France)
- Pharmacology of Neurodegenerative Disorders - Pharmacology-2024 (France)
- Pharmacology of Nutraceuticals and Dietary Supplements - Pharmacology-2024 (France)
- Pharmacology of Pain Management and Analgesia - Pharmacology-2024 (France)
- Pharmacology of Rare Diseases - Pharmacology-2024 (France)
- Pharmacology of Respiratory Diseases: - Pharmacology-2024 (France)
- pharmacotheraphy and drug safety - Pharmacoepidemiology Congress 2024 (Canada)
- Pharmacovigilance and Drug Safety - Clinical-Trials-2024 (Canada)
- Pharmacovigilance and Drug Safety - PHARMA CONFERENCE-2025 (Czech Republic)
- Pharmacovigilance and its Significance - Pharmacoepidemiology Congress 2024 (Canada)
- Pharmacovigilance in the Era of Big Data - Pharmacology-2024 (France)
- Pharmacy Development Services - Pharma Europe 2025 (Italy)
- Pharmacy Education and Practice - PHARMACEUTICAL SCIENCES 2025 (France)
- Photochemistry and Phytopharmaceuticals - PHARMAKON 2025 (Spain)
- Phytochemistry - Natural Products 2024 (Italy)
- Population Health - Personalizedmedicine-2024 (Switzerland)
- Post-Marketing Surveillance Insights - Clinical Trials Congress-2025 (France)
- Post-Trial Closed Communities - Clinical Trials Congress-2025 (France)
- Precision Medicine - Personalizedmedicine-2024 (Switzerland)
- Precision Medicine and Pharmacogenomics - NURSING PHARMACOLOGY 2024 (Netherlands)
- Public Health and Community Nursing - NURSING PHARMACOLOGY 2024 (Netherlands)
- Purpose and Principles of GMP - PHARMACEUTICAL SCIENCES 2025 (France)
- QC & QA: Quality control and Quality assurance - MedTech-2024 (Switzerland)
- Quality by design(QbD) approach - MedTech-2024 (Switzerland)
- Quality Control and Regulatory Considerations in Drug Delivery Systems - Pharmaceutica-2025 (Canada)
- R&D Advancement: Road to New Medicines - PHARMACEUTICAL SCIENCES 2025 (France)
- Radiation-based medicines and biotherapy - Drug Safety 2024 (France)
- Rational Design of Non-Oral Drugs - PHARMA MEDICINAL CHEMISTRY 2025 (Canada)
- Rational Drug Design and Molecular Modeling - PHARMA CONFERENCE-2025 (Czech Republic)
- Real-World Evidence in Clinical Trials - Pharma Europe 2025 (Italy)
- Recent Advancements in Medicinal Pharma - PHARMA MEDICINAL CHEMISTRY 2025 (Canada)
- Reformulation Research - Drug Safety 2024 (France)
- Regenerative Medicine and Tissue Engineering - Drug Delivery-2024 (France)
- Regulatory affairs - Pharmacoepidemiology Congress 2024 (Canada)
- Regulatory Affairs and Drug Safety - PHARMACEUTICAL CHEMISTRY 2025 (Italy)
- Regulatory Affairs and Intellectual Property Rights - Future Pharma 2025 (Netherlands)
- Regulatory Affairs and Quality Assurance in Pharmaceutics - Pharmaceutica-2025 (Canada)
- Regulatory Authority Compliance - MedTech-2024 (Switzerland)
- Regulatory Considerations in Drug Development - Drug Delivery-2024 (France)
- Regulatory Requirements for Pharmaceuticals - PHARMACEUTICAL SCIENCES 2025 (France)
- Regulatory Updates on Biosimilars - Eurobiosimilars 2025 (France)
- Research and development in pharmaceuticals - Drug Safety 2024 (France)
- Research and Trials on Oncology and AIDS - Clinical-Trials-2024 (Canada)
- Risk Management - Pharmacoepidemiology Congress 2024 (Canada)
- Role of Gut Microbiome in Cardiovascular Health - Cardiovascular-2025 (France)
- Role of Inflammation in Cardiovascular Diseases - Cardiovascular-2025 (France)
- Safety of drugs and pharmacovigilance - Drug Safety 2024 (France)
- Smart Drug Delivery Systems - Pharmatech 2025 (Canada)
- Smart Polymers for Drug Delivery - Pharmaceutica-2025 (Canada)
- Sustainability and Global Health Biotechnology - Biotech-2025 (France)
- Synthetic and Bioorganic Chemistry - PHARMACEUTICAL CHEMISTRY 2025 (Italy)
- Targeted Drug Delivery and Controlled Release Systems - PHARMA CONFERENCE-2025 (Czech Republic)
- Targeted Therapies - Personalizedmedicine-2024 (Switzerland)
- Targeted Therapies in Cardiovascular Regeneration - Cardiovascular-2025 (France)
- Targeting the Renin-Angiotensin-Aldosterone System (RAAS) - Cardiovascular-2025 (France)
- Technologies for Formulation - Drug Safety 2024 (France)
- Technology in Pharma Sciences - MedTech-2024 (Switzerland)
- Telemedicine - Personalizedmedicine-2024 (Switzerland)
- The BBB for drug delivery - Drug Safety 2024 (France)
- The Future of Pharma R&D - Future Pharma 2025 (Netherlands)
- The Next Generation Approach of Antibiotics - Antibiotics Resistance 2024 (Canada)
- Therapeutic Drug Transporters - Drug Safety 2024 (France)
- Translational Research - Personalizedmedicine-2024 (Switzerland)
- Translational Research in Pharmacology and Therapeutics - NURSING PHARMACOLOGY 2024 (Netherlands)
- USFDA Approved Biosimilars - Eurobiosimilars 2025 (France)
- Vaccine Delivery Systems - Pharmaceutica-2025 (Canada)
- Vaccine Design and Drug Design - PHARMA CONFERENCE-2025 (Czech Republic)
- Vascular Pharmacology: Focus on Endothelial Dysfunction - Cardiovascular-2025 (France)
- Wearable Drug Delivery Systems - PHARMA CONFERENCE-2025 (Czech Republic)